Welcome to the Neurodiagnostics Laboratory (DIAL) at Charité - Universitätsmedizin Berlin. We work on diagnostic outcomes for autoimmune neurologic diseases like multiple sclerosis or neuromyelitis optica.

To understand disease processes in these often-enigmatic diseases it is quintessential to understand why and how patients develop symptoms. Vice versa, we need to understand how we can measure and analyze problems our patients suffer from most effectively. Only the best possible diagnostic outcome measures will guarantee valid clinical trial results as well as correct and timely diagnosis in clinical care. Furthermore, by understanding what patients suffer from, we can derive information about the underlying disease etiology and approaches for future therapies.

At DIAL, neurologists, neuroimmunologists, and clinical scientists work closely with mathematicians, physicists, biomedical engineers and computational scientists. In this multidisciplinary environment we create and apply technology that is tailored to the clinician’s and clinical scientist’s needs but incorporates latest advances from mathematical and computational domains.

DIAL is a joint institution of the Clinical Neuroimmunology Group at the NeuroCure Clinical Research Center and the Neuroimmunology Service at the Experimental and Clinical Research Center, a joint institution of Charité – Universitätsmedizin Berlin and Max-Delbrück Center for Molecular Medicine.

Alexander U. Brandt, MD
Head, Neurodiagnostics Laboratory


Research Topics


The Afferent Visual System in Autoimmune Neuroinflammatory and Neurologic Disorders

Magnetic Resonance Imaging

MR Imaging Pathology in Autoimmune Neuroinflammatory Disorders

Motor Function

Quantifying and Analysing Motor Dysfunction

Quality of Life

Depression, Fatigue, Pain and Cognitive Dysfunction in Autoimmune Neuroinflammatory Disorders